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| Prostaglandin F2 ： ウィキペディア英語版 |
Prostaglandin F2alpha
Prostaglandin F2α (PGF2α in prostanoid nomenclature), pharmaceutically termed dinoprost (INN), is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.
In domestic mammals, it is produced by the uterus when stimulated by oxytocin, in the event that there has been no implantation during the follicular phase. It acts on the corpus luteum to cause luteolysis, forming a corpus albicans and stopping the production of progesterone. Action of PGF2α is dependent on the number of receptors on the corpus luteum membrane.
The PGF2α isoform ''8-iso-PGF2α'' was found in significantly increased amounts in patients with endometriosis, thus being a potential causative link in endometriosis-associated oxidative stress.
==Mechanism of action==
PGF2α acts by binding to the prostaglandin F2α receptor.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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